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Research Objectives

Deciphering the DNA Code

Deciphering the DNA Code

Using computer science methods to interpret DNA sequences to understand the development, function, growth, and reproduction of organisms.

Understanding Evolution

Understanding Evolution

Compare species differences, explore life's origins, speculate on evolution, and understand the causes of genetic diseases.

Precision Medicine

Precision Medicine

Clinical decisions for disease prevention, diagnosis, and treatment based on a patient's DNA characteristics.

Research Data

DNA sequence data can be obtained from hospitals, companies, and online public databases.

Sequencing machines detect and record DNA for analysis, but their capabilities are limited.

30x

copy sample

0.25%

error rate

9M+

fragments

90GB+

data size

Genomic Visualization

Skills Used

Imagine tearing 30 identical photos into 9 million pieces, with 0.25% damage, and trying to piece them together.

Find similar parts among multiple pictures, sort out important blocks

Solve this complex problem through collaboration.

  • Programming
  • Algorithm
  • Big Data
  • Data Structure
  • Observe
  • Study
  • Analyze
  • Think
  • Logic
  • Express
  • Cooperate
  • Execution

Professor

Professor Yao-Ting Huang

Yao-Ting Huang

Education:
  • Ph.D., CSIE, NTU (2003 ~ 2006)
  • M.S., CSIE, NTU (2001 ~ 2003)
  • B.S., CSIE, NCTU (1997 ~ 2001)
Professional Experience:
  • Professor, CSIE, CCU (2018/8 ~ present)
  • Assistant Professor, CSIE, CCU (2012/8 ~ 2018/7)
  • Asst. Prof., CSIE, CCU, (2007/8 ~ 2012/7)
  • Postdoc, Genomics Center, Academia Sinica (2006/8 ~ 2007/7)
  • Director, TGGS.org.tw, (2017 ~ 2023)
  • Director, TPHTG.org, (2022 ~ 2023)
  • Associate Editor, JISE, (2020 ~ 2023)
Research interest :

We study infectious diseases using NGS/TGS and develop algorithms/software with publications in leading journals including Genome Research, Genome Biology, and Bioinformatics.

Welcome interested students to join our team.

Lab Members

2024
Tzu-Yu Liao

Tzu-Yu Liao

TA Master Bachelor
Email:liaoyoyo2001@gmail.com
Hsu-Fen Fu

Hsu-Fen Fu

TA Master
Email:fushufen9125@gmail.com
Hsu-Hsiang Chiang

Huai-Xiang Jiang

TA Master
Email:c109110123@nkust.edu.tw
2023
Chen Zhen-Yu

Zhen-Yu Chen

Master
Email:puddingchenk@gmail.com
Huang Po-Chung

Bo-Zhong Huang

Master
Email:benson10120@gmail.com
Ho Ming-En

Ming-En He

Master
Email:ianho7236@gmail.com
Lin Ping-Han

Pin-Han Lin

Master
Email:hank06023@gmail.com
Hsieh Chen-Yu

Zhen-Yu Xie

Bachelor
Email:e0979083123@gmail.com
Jin Chen-Han

Chen-Han Jin

Bachelor
Email:hank9185@icloud.com

Lab Activity

Daling Karting

Experience the fun of karting.

2024-09-09

Minxiong goose Dinner

Dinner Eat Minxiong famous goose rice.

2024-07-16

syabu-yo year-end party

Dinner after lab exercise

2024-01-25

Laboratory sports competition

Acceptance of weekly sports results, two-team sports competition.

2024-01-24

ZEPRO Run

Form a "不耀廷" team to participate in road running activities

2023-03-19

Dinner at Zhuju Tea House

Farewell exchange for foreign exchange students

2022-09-29

Lab FAQ

What is bioinformatics?

  • Bioinformatics encompasses all methods that address problems in life sciences using computer science. In recent years, biologists have invented various gene detection chips and high-speed DNA sequencers, generating vast amounts of DNA data. However, each person's DNA consists of about 3 billion nucleotides (A, C, G, T). High-speed computing and software analysis are necessary to decode the mysteries of various life phenomena.

What are the applications of bioinformatics?

  • By designing software to analyze DNA, we can extract complex genetic information hidden within DNA. This can help detect whether we carry hereditary diseases (such as cancer or diabetes) early, reduce the risk of organ rejection, or aid in developing new drugs. Additionally, DNA can help evolutionary biologists unravel the evolutionary history of various species and detect whether species have been influenced by Darwinian evolution.

Do I need biological knowledge?

  • No, you don't. Members of our lab all have information technology backgrounds, and we, along with Wikipedia and Google, will teach you the basics of DNA.

Am I suitable for interdisciplinary research?

  • Bioinformatics spans the fields of life sciences and computer science. This field is more suitable for individuals who are curious, interested in learning and understanding unknown life phenomena, and eager to approach problems from different disciplinary perspectives using various methods.

What research does your lab conduct?

  • Our lab currently focuses on analyzing several types of DNA detection chips, processing high-speed DNA sequencing data, and conducting evolutionary research across different species.
Online Journal

Explore peer-reviewed journals focusing on bioinformatics and computational biology.

Video Tutorials

Watch tutorials on bioinformatics resources to learn fundamental skills from YouTube.

Programs

The laboratory's recent programs focused on research and development can be viewed on GitHub

File Download

Download bioinformatics test data, previously reviewed and publicly available.