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Research Objectives

Deciphering the DNA Code

Deciphering the DNA Code

Using computer science methods to interpret DNA sequences to understand the development, function, growth, and reproduction of organisms.

Understanding Evolution

Understanding Evolution

Compare species differences, explore life's origins, speculate on evolution, and understand the causes of genetic diseases.

Precision Medicine

Precision Medicine

Clinical decisions for disease prevention, diagnosis, and treatment based on a patient's DNA characteristics.

Research Data

DNA sequence data can be obtained from hospitals, companies, and online public databases.

Sequencing machines detect and record DNA for analysis, but their capabilities are limited.

30x

copy sample

0.25%

error rate

9M+

fragments

90GB+

data size

Genomic Visualization

Skills Used

Imagine tearing 30 identical photos into 9 million pieces, with 0.25% damage, and trying to piece them together.

Find similar parts among multiple pictures, sort out important blocks

Solve this complex problem through collaboration.

  • Programming
  • Algorithm
  • Big Data
  • Data Structure
  • Observe
  • Study
  • Analyze
  • Think
  • Logic
  • Express
  • Cooperate
  • Execution

Professor

Professor Yao-Ting Huang

Yao-Ting Huang

Education:
  • Ph.D., CSIE, NTU (2003 ~ 2006)
  • M.S., CSIE, NTU (2001 ~ 2003)
  • B.S., CSIE, NCTU (1997 ~ 2001)
Professional Experience:
  • Professor, CSIE, CCU (2018/8 ~ present)
  • Associate Professor, CSIE, CCU (2012/8 ~ 2018/7)
  • Assistant Professor, CSIE, CCU (2007/8 ~ 2012/7)
  • Postdoc, Genomics Center, Academia Sinica (2006/8 ~ 2007/7)
  • Director, TGGS.org.tw, (2017 ~ 2023)
  • Director, TPHTG.org, (2022 ~ 2023)
  • Associate Editor, JISE, (2020 ~ 2023)
Research interest :

We study infectious diseases using NGS/TGS and develop algorithms/software with publications in leading journals including Genome Research, Genome Biology, and Bioinformatics.

Welcome interested students to join our team.

Lab Members

2025
Photo of Cheng-En Lee

Cheng-En Lee

Bachelor
Photo of Chun-Ting Chang

Chun-Ting Chang

Bachelor
Photo of Ping-Ting Chen

Ping-Ting Chen

TAMaster
Email: rosedog0328@gmail.com
Photo of Yu-Cheng Wu

Yu-Cheng Wu

Bachelor
Photo of Yuan-Ting Chung

Yuan-Ting Chung

Bachelor
Photo of Yung-Jen Yang

Yung-Jen Yang

TAMaster
Email: blackrock88426@gmail.com
2024
Photo of Hsu-Fen Fu

Hsu-Fen Fu

TAMasterAlumni
Email: fushufen9125@gmail.com
Photo of Huai-Xiang Jiang

Huai-Xiang Jiang

TAMasterAlumni
Email: c109110123@nkust.edu.tw
Photo of Tzu-Yu Liao

Tzu-Yu Liao

TAMasterBachelorAlumni
Email: liaoyoyo2001@gmail.com

Lab Activities

Graduation Banquet cover photo

Graduation Banquet

An outdoor banquet in front of the department building to send off our graduating lab members.

2026-06-06
Dinner Gathering cover photo

Dinner Gathering

Dinner with lab alumni, catching up over a round of drinks.

2026-05-02
Lab Sports Day cover photo

Lab Sports Day

Lab sports day featuring volleyball, basketball, and billiards.

2026-01-31
Lab Dinner cover photo

Lab Dinner

Regular lab dinner gathering.

2026-01-29
Lab Exchange in Hong Kong cover photo

Lab Exchange in Hong Kong

Held research discussions with Prof. Luo's lab at The University of Hong Kong, attended the GIW/ISCB-Asia conference, and explored the local culture.

2025-12-10
Attending a Conference cover photo

Attending a Conference

Attended the TGGS conference, presenting posters and exchanging ideas with research groups from other institutions.

2025-12-05
Lab Dinner cover photo

Lab Dinner

Lab dinner gathering.

2025-08-21
Lab Leisure Activity Schedule cover photo

Lab Leisure Activity Schedule

Lab leisure activity planning.

2025-07-31
Photo with Professor and Alumni cover photo

Photo with Professor and Alumni

Group photo with professor and alumni.

2025-06-26
Dinner and Board Games cover photo

Dinner and Board Games

Dinner together and board games.

2025-05-03
Graduation Dinner cover photo

Graduation Dinner

Lab gathering for graduation dinner.

2025-01-22
Group Workout cover photo

Group Workout

Lab group workout.

2025-01-18
Attending a Seminar cover photo

Attending a Seminar

Attended a seminar.

2024-12-14
Alumni Dinner cover photo

Alumni Dinner

Dinner with alumni.

2024-10-27
Dalin Karting cover photo

Dalin Karting

Experienced the thrill of kart racing.

2024-09-09
Minxiong Goose Dinner cover photo

Minxiong Goose Dinner

Graduation gathering enjoying Minxiong’s famous goose dishes.

2024-07-16
Graduation Photo with Seniors cover photo

Graduation Photo with Seniors

Group photo with our graduating seniors.

2024-06-20
Syabu-yo Year-end Party cover photo

Syabu-yo Year-end Party

Post-workout dinner gathering.

2024-01-25
Lab Sports Day cover photo

Lab Sports Day

Two teams competed to wrap up weekly training.

2024-01-24

Lab FAQ

What is bioinformatics?

  • Bioinformatics encompasses all methods that address problems in life sciences using computer science. In recent years, biologists have invented various gene detection chips and high-speed DNA sequencers, generating vast amounts of DNA data. However, each person's DNA consists of about 3 billion nucleotides (A, C, G, T). High-speed computing and software analysis are necessary to decode the mysteries of various life phenomena.

What are the applications of bioinformatics?

  • By designing software to analyze DNA, we can extract complex genetic information hidden within DNA. This can help detect whether we carry hereditary diseases (such as cancer or diabetes) early, reduce the risk of organ rejection, or aid in developing new drugs. Additionally, DNA can help evolutionary biologists unravel the evolutionary history of various species and detect whether species have been influenced by Darwinian evolution.

Do I need biological knowledge?

  • No, you don't. Members of our lab all have information technology backgrounds, and we, along with Wikipedia and Google, will teach you the basics of DNA.

Am I suitable for interdisciplinary research?

  • Bioinformatics spans the fields of life sciences and computer science. This field is more suitable for individuals who are curious, interested in learning and understanding unknown life phenomena, and eager to approach problems from different disciplinary perspectives using various methods.

What research does your lab conduct?

  • Our lab currently focuses on analyzing several types of DNA detection chips, processing high-speed DNA sequencing data, and conducting evolutionary research across different species.
Online Journal

Explore peer-reviewed journals focusing on bioinformatics and computational biology.

Lab Tutorial

Explore the interactive introductory tutorial on long-read cancer genomics.

Programs

The laboratory's recent programs focused on research and development can be viewed on GitHub

File Download

Download bioinformatics test data, previously reviewed and publicly available.